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Premature graying of hair: a concise review

I In a mouse model with a knockout of the Dnmt3b gene, the absence of DNMT3B accelerates the development of lymphoma, indicating that DNMT3B may act as a tumor suppressor gene in normal cells, inhibiting tumor development by stabilizing DNA methylation patterns

Apart from the delivery of small molecular drugs, recent studies have confirmed the same synergistic effect of SeNPs in combination with siRNA for targeted gene silencing as well (Li et al., 2016