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Studies also show that approximately 85% of the population is deficient in B12, and oral supplements are often ineffective in correcting this deficiency

This research shows B12 is important in treating depression

Improvement in Hair Texture Vitamin B12 contributes to the overall health of hair by supporting the production of keratin, a protein that makes up the structure of hair

Researchers conduct most studies in preclinical settings, collect limited human data, and have not yet determined long-term systemic effects

The interest traces to a 2014 Nature paper showing that knocking down NNMT in fat and liver protected mice against diet-induced obesity, glucose intolerance, and fatty liver, partly by shifting adipose NAD+ and SAM levels [4]