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Another mechanism that might be related to corticosteroid resistance, is the activation of c-Jun N-terminal kinase (JNK) by pro-inflammatory cytokines leading to phosphorylation of GR at Ser226 and prevention of binding to GRE

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Mitochondria display critical roles including metabolic homeostasis, redox signaling, regulation of Ca2+, mitochondrial-nuclear communication and cell death (Chen et al., 2023)

GLUTATHIONE adalah protin yang mengandungi 3 jenis asid amino iaitu cysteine, glutamic dan glycine, yang biasanya dihasilkanoleh badan untuk mengatasi pencemaran udara, air yang di minum,bahan kimia dan racun serangga di dalam makanan yang di makan

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