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Harnessing the power of multi-omics approaches offers unprecedented insights into this metabolic diversity, paving the way for innovative therapeutic strategies targeting the metabolic crosstalk within the tumor microenvironment

Chronic ELAM treatment reverses protein S-glutathionylation in the ADP/ATP transport and synthesis pathways Using mass spectrometry, we previously characterized changes in protein abundance, phosphorylation, and S-glutathionylation in muscle and heart from young, aged, and aged chronic ELAM treated mice [12, 13, 24, 25]

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(122) have shown that by encapsulating BDNF, NPs can provide controlled and sustained release, which may enhance the therapeutic efficacy and reduce the frequency of administration