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[44] In the cytosol [edit] Methylcobalamin and 5-methyltetrahydrofolate are needed by methionine synthase in the methionine cycle to transfer a methyl group from 5-methyltetrahydrofolate to homocysteine, thereby generating tetrahydrofolate (THF) and methionine, which is used to make SAMe

Dysautonomia in hypermobile EhlersDanlos syndrome and hypermobility spectrum disorders is associated with exercise intolerance and cardiac atrophy

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Association of mast-cell-related conditions with hypermobile syndromes: a review of the literature