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In biological systems, metal ions are strongly coordinated to aminothiol receptors including proteins and polypeptides

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Nguyen VD, Saaranen MJ, Karala AR, Lappi AK et al (2011) Two endoplasmic reticulum PDI peroxidases increase the efficiency of the use of peroxide during disulfide bond formation

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Among the physiological alterations frequently described in this context, the non-dipping blood pressure pattern is associated with increased arterial stiffness, nocturnal sympathetic overactivity, and the activation of subclinical inflammatory pathways (Tsioufis et al., 2008)