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121 This balance is tightly regulated by brainstem nuclei (e.g., the nucleus tractus solitarius and dorsal motor nucleus) and hypothalamic circuits, integrating baroreceptor and chemoreceptor feedback from the carotid sinus and aortic arch

doi: 10.1016/j.fpsl.2020.100617 112

These findings contribute to developing novel therapeutic strategies targeting AD pathology (Table 11)

Among the GLUTs, GLUT4 is considered the major insulin-regulated glucose transporter protein and is essential for glucose uptake

For patients who have had trouble with missed doses, prior failed tapers, or marked sensitivity to dose changes, smaller percentage reductions are often easier to tolerate, especially as the dose gets lower

However, disease-associated SUOX mutations have revealed that heme binding may not be strictly required for SUOX activity 100