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Hsieh MJ, Lee CH, Chueh HY, et al

In contrast, the AIM-HIGH (Atherothrombosis intervention in metabolic syndrome with low HDL/high triglycerides: impact on global health outcomes) trial, which examined the incremental effect of extended-release nicotinic acid (1.5-2 g/day) on 3,414 patients who had established CVD and atherogenic dyslipidemia and were treated with simvastatin (+/- ezetimibe), provided disappointing results

Therapeutic Goods Administration (TGA) Market, Media and Hype Context Blog detailing FDA warning letter context and vendor enforcement

Muscle tissue burns more calories at rest than fat tissue, so preserving your existing muscle helps maintain metabolic rate even as total body weight decreases

Cagrilintide was engineered from the human amylin backbone with modifications inspired by salmon calcitonin, and it includes a fatty acid chain that enables reversible albumin binding

Dynamic contrast-enhanced magnetic resonance imaging A commonly employed imaging technique to measure subtle BBB permeability is DCE MRI, which utilizes continuous scanning prior to and after injection of an intravenously administered gadolinium-based contrast agent (GBCA) to measure the change in gadolinium concentration in the brain (Heye et al., 2014