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Though investigations will continue exploring the potential of danuglipron, this molecule shows that not every drug candidate will be successful

For suspected macro-B12, precipitation with PEG is the test most often reached for, though it is nonspecific and can remove B12 that is fully available to cells, so direct measurement of the binding proteins, haptocorrin and transcobalamin, may be more informative when it is available

That's why this confusion persists in practices for months, sometimes years, before anyone traces it back to the 90471 vs 96372 distinction

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