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Approximately 1020% of cases present as an autosomal dominant familial form of ALS (FALS), with the remaining cases presenting as a non-inherited, sporadic form of ALS (SALS)

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364 The affected astrocytes demonstrate profound loss of function, in particular impaired K + buffering, 365,366 compromised H + transport, 367 and substantial decrease in glutamate uptake

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Editor information Editors and Affiliations Rights and permissions Copyright information 2017 Springer International Publishing AG, part of Springer Nature About this chapter Cite this chapter Bartoli, C.G., Buet, A., Gergoff Grozeff, G., Galatro, A., Simontacchi, M

Remain well hydrated by consuming plenty of water