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Its remarkable success (with scores of near 90 even in the difficult targets in the 2020 Critical Assessment of Protein Structure Prediction, CASP) was influenced by its training not only on all the PDB structures but also on structures it predicted, and it uses the structure and correlation data to predict the pairs of amino acids that are in contact as well as all amino acid pairwise distances

To help overcome this, the researchers performed a subgroup analysis of specific characteristics shared by individuals within the pooled studies

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doi: 10.1586/1744666X.2015.1012158 [DOI] [PubMed] [Google Scholar] 213