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Although our previous investigation of CDK phosphorylation-defective Fun30 mutants showed defects already in recruitment of the remodeler to DNA damage sites (Bantele et al, 2017), we can at this point not exclude that phosphorylation or complex formation also have an additional role in activating the remodeler in situ at DNA damage sites

You apply sunscreen on any bits of exposed skin every day, all year long, riiight

Conflict of interest statement The authors declared no conflicts of interest in this study

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By reducing lipid hydroperoxides in the presence of ferrous iron, Fer-1 prevents lipid membrane damage and exerts potent anti-ferroptotic effects ( T4, a G-actin sequestering peptide, plays a pivotal role in regulating actin polymerization and is implicated in a wide range of critical biological processes, including cell migration, wound healing, and inflammation ( GB, a terpenoid compound derived from Ginkgo biloba leaves and root bark, is one of the key bioactive constituents known for its therapeutic properties ( Lip-1, a spiroquinoxaline derivative, exhibits potent and selective inhibitory effects on iron-dependent lipid peroxidation pathways, making it a promising candidate for targeting ferroptosis