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The symptoms develop suddenly and include: hives swelling of the face or mouth wheezing fast, shallow breathing a fast heart rate clammy skin anxiety or confusion dizziness vomiting blue or white lips fainting or loss of consciousness If someone has these symptoms: Check whether they are carrying an epinephrine pen

Urgent medical attention is warranted for certain red flag symptoms that may indicate conditions other than RLS

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Some common symptoms may include: Macrocytic Anemia Vitamin B12 deficiency may contribute to macrocytic anemia, a condition involving unusually large red blood cells

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Zhao X, Guan J-L (2011) Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis