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Retatrutide produces mean reductions of 24.2% at the 12 mg dose in Phase 2 research (Jastreboff et al., 2023)

Also, since you need stomach acid to absorb B12, long-term use of acid-suppressing proton pump inhibitors (such as Nexium, etc.) can lead to B12 deficiency, as can chronic intestinal conditions such as Crohns disease, celiac disease, and intestinal parasites

Pain 163 , e738e747 (2022)

Pregnancy and Breastfeeding: Liraglutide is not recommended during pregnancy or breastfeeding due to potential risks and insufficient data on safety

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The review also highlights the relevance of the MM environment, focusing on the importance of the bone marrow (BM) niche