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The identified genes were categorized into three groups: 1) genes likely involved in housekeeping functions manifesting pleiotropic effects on multiple metabolites, 2) genes previously known to be involved in pathways for metabolites, and 3) novel genes which we have now genetically linked to specific metabolic pathways for metabolites

MTHFR can inhibit ferroptosis by blocking the ubiquitination of HMOX1

Neuron 13, 12251233.10.1016/0896-6273(94)90060-4 82 MoriokaI.WongR

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