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Thus, lower expression of this transport channel could decrease the amount of intracellular cisplatin and could explain the resistance of the U138MG cells

The MGSTs and LTC4S catalyze conjugation reactions to GSH

doi: 10.7759/cureus.29696

In other words, injections are more precise in addition to being more efficient than other means

[1] For B vitamin supplementation in situations where homocysteine is above 6, try using the following doses to ameleorate: Pyridoxal-5-phosphate (P5P) form of vitamin B6, 20-50 mg/day Methylcobalamin (methyl-B12) and adenosylcobalamin forms of B12, 1mg/day Methyltetrahydrofolate (methyl-folate) form of folate, starting with 0.8/day, with a max of 5mg/day Check your homocysteine again after 3 months to see if homocysteine has dropped to 6 micromoles per liter or lower