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Clinical description All patients with 5-oxoprolinase deficiency have been identified because of 5-oxoprolinuria (4 to 10 g/day

Statements Author contributions AEP conceived the idea, surveyed the literature and wrote the manuscript

Badania przeprowadzone przez Pickarta i jego zesp wykazay, e peptyd ten ma zdolno do przywracania ekspresji genw w komrkach starzejcych si do poziomu charakterystycznego dla modych komrek

doi: 10.1016/j.biopha.2022.113386

doi:10.1007/s13300-019-0619-1 33

300 As mentioned earlier, H 2 O 2 expression results in dimerization and subsequent initiation of ASK1, which initiates p38 MAPK and JNK, stabilizing p53