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In a high quality 28-day study in 34 women with mild to moderate constipation, taking 1.5 grams (g) of magnesium oxide per day significantly improved stool consistency, quality of life, and the time it took digested food to move through the colon, compared with a placebo ( Studies have also shown that magnesium citrate and mineral water containing magnesium sulfate helped treat constipation ( Keep in mind that magnesium sulfate may cause digestive side effects such as bloating and diarrhea

Significant changes in the subscale of inappropriate speech were observed at the assessment time points between 8 and 15 weeks (SMD = -1.13, 95% CI: -2.14 to -0.11, P = 0.03)

Availability of data and materials Data described in the manuscript will be available upon request and approval by the UK Biobank ( References Oppenheimer GM, Benrubi ID