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Gynecomastia, characterized by breast enlargement, occurs in 44% of cirrhosis cases, also due to elevated estrogen levels, and is related to conditions like extreme obesity, hypogonadism, and various adrenal and testicular diseases (88, 89)

Isolated knowledge of individual elements (e.g., neurons, glia, or vascular cells) is insufficient to predict long-term physiological adaptations or pathological cascades (Virtuoso et al

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