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Methodology: D.Z., Q.M.P., A.S., C.W

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After vortexing for 1 min at 48 C and incubated for 4 h at 80 C, the samples were then centrifuged at 14,000 g for 10 min at 4 C

The purpose of our work was to elucidate whether BG affects pathways prior to DNA damage (i.e., glutathione, GSH) or following DNA damage (i.e., nucleotide excision repair, NER)

Interestingly, recent studies have shown that extracellular Glu can stimulate Ca 2+ release from the astrocytic intracellular stores, further triggering Glu release from astrocytes to the adjacent neurons via an exocytotic mechanism (Mahmoud et al., 2019)