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Moreover, SLE patients with lower DUSP22 expression levels in peripheral blood T cells show poor renal outcome, indicating that downregulation of DUSP22 is a prognostic biomarker of SLE nephritis [110]

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In SPR-based sensors, antibodies are immobilized on a gold surface, and the binding of EVs to these antibodies induces changes in the refractive index near the sensor surface, resulting in a detectable SPR signal (Reiner et al., 2017)

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