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Description

HMGB1 contains three redox sensitive cysteine residues and carries out different immune system roles depending on its redox state

Outcomes were measured using PROMIS T-scoresvalidated, widely used patient-reported outcome instruments: Pain Intensity: 65.0 58.7 ( 6.3, p 98 percent purity via HPLC/MS, third-party testing for heavy metals and microbial contamination, and documentation of raw material endotoxin levels

10.1074/jbc.M109.069591 J

However, within this assay, the robustness for post-fortified DBS samples (from blank samples with different Hct) was studied, since the smallest volume of non-coagulated capillary blood that could be obtained from the fingertip was not suitable for mixing with the standard before spotting onto the DBS card