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When determining the Alanine to Lysine ratio as an indirect measure of mitochondrial distress we found that unaffected children had an average ratio of 5.8 and those with konzo have an average ratio of 6.9, both of which are substantially higher than the expected ratio of less than 3 for healthy adolescents (Fig

Moore KJ, Kunjathoor VV, Koehn SL, Manning JJ, Tseng AA, Silver JM, McKee M, Freeman MW

View on PubMed Some Pharmacological Effects of Delta-sleep-inducing Peptide (DSIP) Characterised DSIP pharmacology in preclinical models, showing effects on sleep architecture, circadian rhythm regulation, and interaction with endogenous sleep-promoting systems (Eur Neurol, 1984)