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The multiple faces of proteinkinase R in antiviral defense

363 Also, m-aconitase activity can contribute to the proliferation and migration of prostate cancer cells

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Ferroptosis has been shown to follow a different cell death pathway from apoptosis and thus is attracting attention as a new target for cancer therapy

N Engl J Med 290:13991402 Krauskopf J, Caiment F, Claessen SM, Johnson KJ, Warner RL, Schomaker SJ, Burt DA, Aubrecht J, Kleinjans JC (2015) Application of high-throughput sequencing to circulating microRNAs reveals novel biomarkers for drug-induced liver injury

299 The pathogenesis of AD is often linked to insulin resistance, with PI3K playing a central role in insulin signaling, including GLUT translocation, glycogen synthesis, lipid and protein synthesis, anti-lipolytic effects, and hepatic gluconeogenesis