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Examples of these molecules are Resolvin E1, PDGF, Galectin-1, Alpha-arbutin and Nicotinamide 175,176,177,178,179

Current treatment guidelines support the use of methylcobalamin (MC), a methylated derivative of vitamin B 12 which also demonstrates efficacy in improving nerve conduction and reducing neuropathic pain 9 , but thus far, the clinical value of MC has not been studied in comparison to ALC