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This dysregulation is especially problematic in the case of critical illness when a lack of Se might worsen NTIS because thyroid hormones are not regulated adequately to meet the needs of metabolism [52]

CRISPR/Cas9 approach is being applied nowadays to target the editing of potential candidate genes, which enhance plant resistance against fungal pathogens (Schloss and Handelsman, 2004)

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Commonly suggested biomedical hypotheses to explain PAIS (such as in long COVID/PASC, ME/CFS) are chronic stimulation of the immune system by a persistent infection or persistent unviable pathogen structures