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This paper reviews the research of TIGAR in neurological diseases, including stroke, Parkinsons disease (PD), Alzheimers disease (AD), seizures and brain tumors, aiming to provide reference for the development of new therapeutic targets

Similarly, Semax , a synthetic peptide with nootropic properties, has been shown to increase brain-derived neurotrophic factor (BDNF) and dopamine function, potentially improving cognitive flexibility and emotional regulation in individuals affected by long-term substance use (Myasoedov et al., 2013)

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published in Trends in Molecular Medicine (2005) characterized Thymosin Beta-4 as an actin-sequestering protein that moonlights to repair injured tissues, establishing the foundational mechanism for TB-500s regenerative activity