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Interestingly, low GSH levels (and high oxidant burdens) are associated with many immune dysfunctions, including auto-immune and inflammatory diseases such as Rheumatoid Arthritis, Crohns disease, multiple sclerosis, and psoriasis

The 12-week trial also found that lower doses of PT-141 (1.25mg) were effective but to a much lesser extent, with women reporting a +0.7 increase on average [5]

pmid:22221307 3

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FSP1, as an oxidoreductase, can reduce CoQ10 on the cell membrane, produce lipophilic free radical scavenging antioxidants, and prevent the increase of LPO (Bersuker et al., 2019)