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Neuroprotective effect of diosgenin in a mouse model of diabetic peripheral neuropathy involves the Nrf2/HO-1 pathway

If your supply is decreased, you will have decreased detoxification of toxins

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Role of pharmacokinetics and metabolism in drug discovery and development

We can see a large number of articles using glutamate modeling to study the mechanism of excitotoxicity, most of which only look at the increase in calcium ions and mitochondrial dysfunction caused by excitotoxicity