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Nitrous oxide, aka laughing gas, is commonly used for sedation and pain relief, but it is also widely abused for its ability to induce a very brief high

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As a result, at the end-stage, the failing heart contains about 30% less ATP than a healthy heart and also exhibits a lower PCr content [143], PCr being generated by creatine kinase from ATP and acting as an energy storage molecule and an energy transport compound (for further details see [144])

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