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GPX3 is a typical N-terminal pilot sequence, but lacks endoplasmic reticulum (ER) preserved signal

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Finally, ferroptosis-related genes deregulation in glial cells seems to be associated with later stages of tau-associated AD pathology, as not only more DEGs could be observed with increased pathology, reflected by a higher Braak stage, but also more cell types were affected by AD pathology (number of DEGs in 0 vs

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doi: 10.3389/fmicb.2022.826487 231

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However, the oxidation of cholesterol in the SV membrane decreases the involvement of these SVs in subsequent rounds of neurotransmitter release (Zakirjanova et al., 2023)

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