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Experimental infusion of defined pathogen consortia into the uterus has successfully reproduced endometritis phenotypes, providing direct evidence for a causal role of microbial imbalance in uterine pathology 130

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doi:10.1073/pnas.94.24.12786

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These perhaps most significant findings regarding DSIP have been confirmed in other studies, which have shown that DSIP improves sleep structure and efficiency, and reduces sleep latency in chronic insomnia compared to placebo