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this renders the enzyme essentially inactive in metabolizing acetaldehyde to acetic acid

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Why ALA and benfotiamine work well together ALA is widely recognized for its ability to reduce oxidative stress, improve microcirculation, and relieve symptoms of diabetic neuropathy, including burning, tingling, and pain.17 Benfotiamine, a fat-soluble derivative of vitamin B1 (thiamine), helps reduce the formation of advanced glycation end products (AGEs), which are major contributors to nerve damage in diabetes.46 Some research shows that combining ALA with benfotiamine can result in greater symptom improvement than using either compound alone.47 And while benfotiamine alone has produced mixed results, its well-tolerated and is potentially more effective when stacked with ALA.53 Pricing, subscriptions, and shipping A single bottle (120 capsules) costs $22.94, including $3.95 shipping, and lasts 60 days at the standard two-capsule dose

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