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LXR activation increases liver and plasma TG and LDL-C in animal models 14,15,16,17 and humans 18 by upregulating DNL genes 10 , including SREBF1 , ACACA and FASN , and suppressing hepatic LPL activity by inducing ANGPTL3 and APOC3 (ref

World journal of gastroenterology, 28(1), 2346

Kaur C, Kushwaha HR, Mustafiz A, Pareek A, Sopory SK, Singla-Pareek SL

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