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10.3389/fimmu.2022.999407 91 JovanovicF.SudhakarA.KnezevicN

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66 These findings demonstrate that GSH buffers antibiotic-generated oxidative stress, whereas a deficiency in GSH or an overload of ROS renders bacteria significantly more vulnerable

Cells were collected at 500 x g for 5 minutes then washed once in PBS

Glutathione (GSH), often referred to as the body's master antioxidant, plays a critical role in detoxification and immune function

Finally, one study (NCT05553834) is testing a therapeutic combination of alirocumab, a PCSK9 inhibitor, with cemiplimab, a PD-1 checkpoint inhibitor, to determine whether it can improve the characteristics of the NCSLC immune microenvironment and thus the overall efficacy of treatment