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The glial cell proliferation and other phenomena reported in early studies were caused by the intracerebroventricular injection of ultra-high doses of GDNF (4 mg per patient), which is not a common effect under clinically reasonable doses [115, 116]

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These ratiometric data were normalised to measurements of cells treated with 10 mM CHP (Sigma-Aldrich, St

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Specifically, treatments with CoQ10 and Vit C, either individually or in combination, were administered for 10 days preceding the sepsis induction

Pereira et al