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Non-coding RNAs Non-coding RNAs (ncRNAs) represent a broad category of RNA molecules that lack the protein coding potential but instead regulate gene expression at several levels

2.4 Inflammation Astrocytes and microglia critically contribute to maintaining a homeostatic balance in the CNS by regulating immune responses with production of cytokines and inflammatory mediators

doi: 10.3109/10409238.2011.557713

de Koning-Ward, T

Humans and rodents possess four PDK isozymes (PDK1-4), with PDK2 and PDK4 (PDK2/4) exhibiting a more generalized tissue distribution and being significantly associated with metabolic disorders compared to PDK1 and PDK3 (135, 136)

[3] In these conditions: the rate of pyruvate production via glycolysis exceeds the rate of its oxidation through the citric acid cycle , so that less than 10% of the pyruvate enters the cycle