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8A shows large intracellular A aggregates in old-age 3xTg-AD neurons detected by binding of an A aggregation-specific antibody mOC78 (Fig

Davies, A

353,354 The other method is the endogenous pathway, which uses the endogenous pathway of exosome generation to indirectly improve the production of exosomes by promoting the expression of target nucleic acids and exosome secretion in productive cell lines

doi: 10.1016/S0891-5849(00)00487-1

elevated oxidative damage markers like 8-hydroxy-2-deoxyguanosine (8-OHdG) and 4-hydroxynonenal (4-HNE) have been detected in the auditory centers and hippocampus of tinnitus patients and animal models, indicating systemic oxidative injury (Scuto et al., 2020