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Proposed Mechanistic Model of ALC in Depression and Stress-Related Modulation ALC may exert antidepressant effects through converging mechanisms including mitochondrial bioenergetic enhancement, epigenetic upregulation of mGlu2 expression, and reduction of neuroinflammation

Transfection of Cpt1a siRNA significantly reduced Cpt1a gene expression ( Figure 4D )

16 Canine obesity is an epidemic similar to that seen in humans: approximately 50% of pet dogs have been estimated to be obese based on several epidemiological studies

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Losing hair is a natural phenomenon: each day, it is normal to lose 50 to 100 hairs