Evidence for mitochondrial dysfunction in acquired epilepsy comes from the observation that metabolic and bioenergetic changes occur following acute seizures and during different phases of chronic epilepsy (68)
Zhou Z, Niu H, Bian M, Zhu C
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This response, mediated predominantly by innate immunity, is responsible for elimination of these injurious stimuli and for the subsequent healing process
It emphasizes mitophagys potential in treating brain injuries, including reducing cell damage, promoting cell recovery, and improving neurological function, thus opening new perspectives and directions for future research and clinical applications
