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Maternal Mthfd1 disruption impairs fetal growth but does not cause neural tube defects in mice

Therefore, it is extremely important

The diet is highly restrictive and includes lean proteins (such as chicken breast, fish, and lean beef), specific vegetables (such as spinach, lettuce, and cucumbers), and limited fruits (such as apples, strawberries, and oranges)

In experiments, it has also been safe on animals at any dose administered (Pollard BJ, 2001)

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On the other hand, Dave and coworkers found a disruption of the Calu3 ALI monolayer infected with R001, N222.1, and N459.6 meningococcal strains, suggestive of a paracellular route of epithelial crossing (Dave et al., 2023)