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Cur significantly inhibited the biosynthesis of spermine and spermidine by decreasing the expression of ornithine decarboxylase (ODC) and suppressed D-glutamine metabolism, which in turn decreased the anti-oxidative stress ability and P-gp transport activity of SW620/Ad300 cells, eventually reversed MDR

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4 Discussion 4.1 Infection with SARS-CoV-2 or Cpn may contribute to AD pathogenesis While the exact pathology of AD is unclear, there is evidence to suggest that its development may be linked to inflammation of neuronal tissue, specifically in the limbic system

Molecular Therapy The Journal of the American Society of Gene Therapy 21 (1), 185191

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