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Vegetarians and vegans can especially benefit from L-carnitine supplements, as can older adults, as carnitine levels in the body decline as men age

PLoS ONE 7:e40881 Muoio DM, Noland RC, Kovalik JP, Seiler SE, Davies MN, DeBalsi KL, Ilkayeva OR, Stevens RD, Kheterpal I, Zhang J, Covington JD, Bajpeyi S, Ravussin E, Kraus W, Koves TR, Mynatt RL (2012) Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility

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However, it is important to emphasize that these results cannot be attributed to L-carnitine alone: the observed efficacy relies on a cream combining multiple actives (L-carnitine, licochalcone A, and decanediol) and on its use in conjunction with photodynamic therapy

In a study out of Australia published in the International Journal of Sports Nutrition and Exercise Metabolism , for instance, 36 obese women took either L-carnitine or a placebo and completed eight weeks of aerobic training