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This work shows that the differential effect of force on integrinfibronectin unbinding (catch bond) and on talin unfolding (slip bond) leads to a mechanosensing mechanism, which allows talin unfolding only when cells are seeded on stiff substrates

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10 , e018799 (2021)

Access this article Similar content being viewed by others References Akar S, Harmankaya I, Ugras S, Celik C (2019) Nicotinamide N -methyltransferase expression and its association with phospho-Akt, p53 expression, and survival in high-grade endometrial cancer