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gasseri prevented dexamethasone (DEX)-induced muscle atrophy by stimulating myogenesis and protein synthesis through activation of the IGF-1-PI3K/AKT/mTOR pathway, reducing protein breakdown via FOXO-mediated modulation of the ubiquitin-proteasome pathway (UPP) and autophagy lysosomal pathway (ALP)

PubMed Yarrington CD, Pearce EN

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10.1038/nature05859 93 YangW

An increased toxic burden in cell membranes contributes to the collateral damage and persistent symptoms people experience in chronic diseases