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Following mRNA delivery by the SLN, sustained gene expression in the RPE lasted for up to 5 days [194]

The search terms included macrophages, polarization, metabolic reprogramming, mitochondrial function, endoplasmic reticulum (ER) stress, mechanotransduction, epigenetic regulation, and signaling pathways

However, under cellular conditions, the concentration (110 mM) of GSH is several folds higher than of hydroperoxides (10100 M), and thus, the velocity ( V max ) of the detoxification of hydroperoxides by seleno-GPxs is practically independent of the concentration of GSH [8, 17, 18]

Rana I, Khan N, Ansari M et al (2020) Solid lipid nanoparticles-mediated enhanced antidepressant activity of Duloxetine in lipopolysaccharide-induced depressive model