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I first heard about this on one of Hubermans shows

The pMET protein levels peak at P7P14 in the neocortex, a period corresponding to synaptogenesis and dendritic outgrowth, and are downregulated during the 3rd post-natal week, between P14 and P17, when pruning and functional synapse maturation occur (Eagleson et al., 2016)

Important Safety Information : Tirzepatide carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

Rodriguez-Pint I, Agmon-Levin N, Howard A, Shoenfeld Y

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ARA-290 has the strongest specific evidence for SFN, with human clinical trials demonstrating measurable nerve fiber regrowth in the cornea of SFN patients