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Based on the working hypothesis of P-gp-dependent collateral sensitivity [14,15,16,17], we examined the ability of tamoxifen as a collateral sensitivity drug for two reasons: a) tamoxifen has been previously shown to activate P-gp ATPase at clinically achievable concentration (46 M) [20, 21], and b) tamoxifen is widely used in the treatment of estrogen receptor-positive breast cancer [22]

Luanpitpong S, Chanvorachote P

(More information) Insufficient iodine intake impairs the production of thyroid hormones, leading to a condition called hypothyroidism

Chronic administration of fluoxetine and pro-inflammatory cytokine change in a rat model of depression

The entire procedure was performed under sterile conditions, including the use of sterilized gloves and pre-sterilized cryovials

has received consulting and speaking fees from AbbVie, Janssen, Pfizer, Celltrion and Takeda