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One of the treatments utilising corticosteroids is effective in controlling the symptoms, but cannot be used for the long term due to the side effects that include effects on weight, bone mass and blood pressure

Despite the immunosuppressive microenvironment of lymphangiogenic tumors mediated in part by LEC antigen presentation-induced T cell tolerance (94, 95, 98), they are more sensitive to systemic immunotherapy due to the elevation of CCL21 in LECs, which promotes the retention of nave T cells and DCs in lymphangiogenic tumors via CCL21/CCR7 chemokine axis (100)

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Fc polypeptide molecules can be obtained by pepsin digestion of an immunoglobulin molecule, for example and not limitation

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A key limitation of sequencing-based approaches targeting live cells after effective biocide treatment is the typically low biomass, which can constrain the number of successful replicates and reduce sequencing depth