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Oral administration is possible in preclinical research

Current Pharmaceutical Design , 26(18), 29032922

Short in plasma, but extended tissue activity through binding to the actin pool Subcutaneous or intramuscular

[DOI] [PMC free article] [PubMed] [Google Scholar] 78.Wu KL, Chaikomin R, Doran S, Jones KL, Horowitz M, Rayner CK

Dimethyl fumarate induces necroptosis in colon cancer cells and the mechanism involves GSH depletion, an increase in ROS and activation of MAPKs-mediated signalling [1]